[CAS NO. 106-25-2]  Nerol

Nerol possesses a possible anxiolytic effect in mice. In the open field test, groups treated with nerol show a significant decrease in motor activity (number of crossings, rearings and groomings) when compared with vehicle group. In the elevated plus-maze test, nerol groups significantly increase the number of entries and time of permanence in the open arms. In the light-dark test, nerol groups show a significant increase the time of permanence in the room clear when compared with vehicle group. In the rota rod test, the groups treated with nerol do not show modification in time spent and number of falls in the revolving bar when compared with vehicle group.