[CAS NO. 1258226-87-7] Ombitasvir (ABT-267)

Name: Ombitasvir (ABT-267)
Brand: Arctom Scientific
SKU: SLK-S5403

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PRODUCTS SPECIFICATIONS [1258226-87-7]

Store

Catalog

SLK-S5403

Brand

Selleck

CAS

1258226-87-7

DESCRIPTION [1258226-87-7]

Overview

MDL	MFCD28386270
Molecular Weight	894.11
Molecular Formula	C50H67N7O8
SMILES	C(C)(C)(C)C1=CC=C(N2[C@@](CC[C@]2(C3=CC=C(NC(=O)[C@H]4N(C([C@@H](NC(OC)=O)C(C)C)=O)CCC4)C=C3)[H])(C5=CC=C(NC(=O)[C@H]6N(C([C@@H](NC(OC)=O)[C@@H](C)C)=O)CCC6)C=C5)[H])C=C1

For research use only.

Storage

3 years,-20°C,powder
1 years,-80°C,in solvent

Shipping

Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)

Description

Ombitasvir (ABT-267) is an inhibitor of the HCV non-structural protein 5A with antiviral activity.

Targets

NS5A ^[1]

In vitro

Ombitasvir (ABT-267) is a hepatitis C virus (HCV) NS5A inhibitor with picomolar potency, pan-genotypic activity, and 50% effective concentrations (EC50s) of 0.82 to 19.3 pM against HCV genotypes 1 to 5 and 366 pM against genotype 6a. Ombitasvir has EC50s of 14.1 and 5.0 pM against genotype 1a-H77 and 1b-Con1 subgenomic replicons, respectively.

References

[1] Krishnan P, et al. Antimicrob Agents Chemother. 2015, 59(2):979-87.

Synonyms

L-Prolinamide, 2,2′-[[(2S,5S)-1-[4-(1,1-dimethylethyl)phenyl]-2,5-pyrrolidinediyl]di-4,1-phenylene]bis[N-(methoxycarbonyl)-L-valyl-

2,2′-[[(2S,5S)-1-[4-(1,1-Dimethylethyl)phenyl]-2,5-pyrrolidinediyl]di-4,1-phenylene]bis[N-(methoxycarbonyl)-L-valyl-L-prolinamide]

ABT 267

Ombitasvir