[CAS NO. 1113-59-3] Bromopyruvic acid

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PRODUCTS SPECIFICATIONS [1113-59-3]

Catalog

SLK-S5426

Brand

Selleck

CAS

1113-59-3

DESCRIPTION [1113-59-3]

Overview

MDL	MFCD00002587
Molecular Weight	166.96
Molecular Formula	C3H3BrO3
SMILES	C(C(O)=O)(CBr)=O

For research use only.

Storage

3 years,-20°C,powder
1 years,-80°C,in solvent

Shipping

Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)

Preparing Stock Solutions

Concentration Volume Mass	1 mg	5 mg	10 mg
1 mM	5.9895 mL	29.9473 mL	59.8946 mL
5 mM	1.1979 mL	5.9895 mL	11.9789 mL
10 mM	0.5989 mL	2.9947 mL	5.9895 mL
50 mM	0.1198 mL	0.5989 mL	1.1979 mL

Description

Bromopyruvic acid (3-Bromopyruvic acid, 3-Bromopyruvate, Bromopyruvic acid, Hexokinase II Inhibitor II, 3-BP) is a inhibitor with Ki of 2.4 mM for glycolysis/hexokinase inhibition. It is inhibitor of tumour cell energy metabolism and chemopotentiator of platinum drugs.

In vitro

Bromopyruvic acid, a glycolysis inhibitor, maintains haploidy to a certain extent in both OdG and EG1 haESCs, with no effect on the proliferation or pluripotency of the haESCs.

References

[1] Linda StrandbergIhrlund, et al. Molecular Oncology. 2008, 2(1):94-101.
[2] Zhang G, et al. Stem Cell Reports. 2021;16(1):29-38.
[3] Fang Y, et al. Nat Commun. 2019 Sep 4;10(1):3981.

Synonyms

Propanoic acid, 3-bromo-2-oxo-

Pyruvic acid, bromo-

3-Bromo-2-oxopropanoic acid

Bromopyruvic acid

β-Bromopyruvic acid

3-Bromopyruvic acid

3-Bromopyruvate

NSC 11731

NSC 62343

3-Bromo-2-oxo-propionic acid