[CAS NO. 51022-69-6] Amcinonide

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PRODUCTS SPECIFICATIONS [51022-69-6]

Catalog

SLK-S5671

Brand

Selleck

CAS

51022-69-6

MDL	-
Molecular Weight	502.57
Molecular Formula	C28H35FO7
SMILES	C(COC(C)=O)(=O)[C@]12[C@]3(C)[C@@](C[C@]1(OC4(O2)CCCC4)[H])([C@]5([C@](F)([C@@H](O)C3)[C@]6(C)C(CC5)=CC(=O)C=C6)[H])[H]

For research use only.

3 years,-20°C,powder
1 years,-80°C,in solvent

Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)

Amcinonide (Cyclocort, CL-34699) is an inhibitor of release from activated microglia with IC50 of 3.38 nM.

NO ^[1]
(Cell-free assay)

3.38 nM

Amcinonide treatment leads to a significant up-regulation of Gli1 expression, while all the other compounds tested have minor or no effects.

Pregna-1,4-diene-3,20-dione, 21-(acetyloxy)-16,17-[cyclopentylidenebis(oxy)]-9-fluoro-11-hydroxy-, (11β,16α)-

Spiro[cyclopentane-1,8′-[2H]naphth[2′,1′:4,5]indeno[1,2-d][1,3]dioxole], pregna-1,4-diene-3,20-dione deriv.

(11β,16α)-21-(Acetyloxy)-16,17-[cyclopentylidenebis(oxy)]-9-fluoro-11-hydroxypregna-1,4-diene-3,20-dione

Amcinonide

Visderm

Cyclocort

CL 34699

Amciderm

Penticort