[CAS NO. 81147-92-4] Esmolol

Name: Esmolol
Brand: Arctom Scientific
SKU: SLK-S5778

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PRODUCTS SPECIFICATIONS [81147-92-4]

Distributor

Catalog

SLK-S5778

Brand

Selleck

CAS

81147-92-4

DESCRIPTION [81147-92-4]

Overview

MDL	-
Molecular Weight	295.37
Molecular Formula	C16H25NO4
SMILES	O(CC(CNC(C)C)O)C1=CC=C(CCC(OC)=O)C=C1

For research use only.

Storage

3 years,-20°C,powder
1 years,-80°C,in solvent

Shipping

Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)

Preparing Stock Solutions

Concentration Volume Mass	1 mg	5 mg	10 mg
1 mM	3.3856 mL	16.9279 mL	33.8558 mL
5 mM	0.6771 mL	3.3856 mL	6.7712 mL
10 mM	0.3386 mL	1.6928 mL	3.3856 mL
50 mM	0.0677 mL	0.3386 mL	0.6771 mL

Description

Esmolol is a cardioselective blocker with rapid onset, a very short duration of action, and no significant intrinsic sympathomimetic or membrane stabilising activity at therapeutic dosages.

Targets

Human β1-Receptor ^[1]	Human β2-Receptor ^[1]
194 nM(Ki)	5.8 μM(Ki)

In vitro

Esmolol acts as a pharmacochaperone: Long term exposure of cells to esmolol raised the surface levels of β1-adrenergic receptors.

References

[1] Nasrollahi-Shirazi S, et al. J Pharmacol Exp Ther. 2016, 359(1):73-81.

Synonyms

Benzenepropanoic acid, 4-[2-hydroxy-3-[(1-methylethyl)amino]propoxy]-, methyl ester

Esmolol

ASL 8052-001

(±)-Esmolol

3-(4-(2-Hydroxy-3-(isopropylamino)propoxy)phenyl)propionic acid methyl ester