[CAS NO. 84449-90-1] Raloxifene

Name: Raloxifene
Brand: Arctom Scientific
SKU: SLK-S5781

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PRODUCTS SPECIFICATIONS [84449-90-1]

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Catalog

SLK-S5781

Brand

Selleck

CAS

84449-90-1

DESCRIPTION [84449-90-1]

Overview

MDL	-
Molecular Weight	473.58
Molecular Formula	C28H27NO4S
SMILES	C(=O)(C1=C(SC=2C1=CC=C(O)C2)C3=CC=C(O)C=C3)C4=CC=C(OCCN5CCCCC5)C=C4

For research use only.

Storage

3 years,-20°C,powder
1 years,-80°C,in solvent

Shipping

Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)

Preparing Stock Solutions

Concentration Volume Mass	1 mg	5 mg	10 mg
1 mM	2.1116 mL	10.5579 mL	21.1158 mL
5 mM	0.4223 mL	2.1116 mL	4.2232 mL
10 mM	0.2112 mL	1.0558 mL	2.1116 mL
50 mM	0.0422 mL	0.2112 mL	0.4223 mL

Description

Raloxifene (Keoxifene, Pharoxifene, LY-139481, LY-156758, CCRIS-7129) is a second generation selective modulator (SERM) used to prevent osteoporosis in postmenopausal women.

Targets

ER ^[1]
(Cell-free assay)

5.7 nM

References

[1] Obach RS, et al. Drug Metab Dispos, 2004, 32(1), 89-97.

Synonyms

Methanone, [6-hydroxy-2-(4-hydroxyphenyl)benzo[b]thien-3-yl][4-[2-(1-piperidinyl)ethoxy]phenyl]-

[6-Hydroxy-2-(4-hydroxyphenyl)benzo[b]thien-3-yl][4-[2-(1-piperidinyl)ethoxy]phenyl]methanone

LY 139481

Keoxifene

Raloxifene

[2-(4-Hydroxyphenyl)-6-hydroxybenzo[b]thien-3-yl][4-(2-(1-piperidinyl)ethoxy)phenyl]methanone

[6-Hydroxy-2-(4-hydroxyphenyl)-1-benzothiophen-3-yl]-[4-(2-piperidin-1-ylethoxy)phenyl]methanone

2-(4-Hydroxyphenyl)-3-[4-[2-(piperidin-1-yl)ethoxy]benzoyl]-1-benzothiophen-6-ol