[CAS NO. 912545-86-9]  Smoothened Agonist (SAG)

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PRODUCTS SPECIFICATIONS [912545-86-9]

Catalog
SLK-S6384
Brand
Selleck
CAS
912545-86-9

DESCRIPTION [912545-86-9]

Overview

MDLMFCD22581513
Molecular Weight490.06
Molecular FormulaC28H28ClN3OS
SMILESN(C(=O)C1=C(Cl)C=2C(S1)=CC=CC2)(CC3=CC(=CC=C3)C=4C=CN=CC4)[C@@H]5CC[C@@H](NC)CC5

For research use only.

Storage

3 years,-20°C,powder
1 years,-80°C,in solvent

Shipping

Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)

Targets

Smo [1]
(in Shh-LIGHT2 cells)
3 nM(EC50)

In vitro

SAG can counteract glucocorticoids (GCs) antagonism of Shh-driven granule neuron precursor (CGNP) proliferation.


Synonyms

Benzo[b]thiophene-2-carboxamide, 3-chloro-N-[trans-4-(methylamino)cyclohexyl]-N-[[3-(4-pyridinyl)phenyl]methyl]-
3-Chloro-N-[trans-4-(methylamino)cyclohexyl]-N-[[3-(4-pyridinyl)phenyl]methyl]benzo[b]thiophene-2-carboxamide
SAG
SAG (cyclopamine antagonist)
SAG (Smo agonist)
Smoothened Agonist