[CAS NO. 646502-53-6] VcMMAE
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PRODUCTS SPECIFICATIONS [646502-53-6]
Catalog
SLK-S6661
Brand
Selleck
CAS
646502-53-6
DESCRIPTION [646502-53-6]
Overview
| MDL | MFCD25372036 |
|---|---|
| Molecular Weight | 1316.63 |
| Molecular Formula | C68H105N11O15 |
| SMILES | CC[C@]([H])(C)[C@@]([H])([C@@]([H])(CC(N1CCC[C@]1([C@@]([H])([C@@]([H])(C)/C(O)=N/[C@]([H])(C)[C@]([H])(C2=CC=CC=C2)O)OC)[H])=O)OC)N(C)C([C@]([H])(C(C)C)/N=C([C@]([H])(C(C)C)N(C)C(OCC3=CC=C(C=C3)NC([C@]([H])(CCCNC(O)=N)/N=C([C@]([H])(C(C)C)/N=C(CCCCCN4C(C=CC4=O)=O)\O)\O)=O)=O)\O)=O |
For research use only.
Storage
3 years,-20°C,powder
1 years,-80°C,in solvent
1 years,-80°C,in solvent
Shipping
Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)
Preparing Stock Solutions
| 1 mg | 5 mg | 10 mg | |
| 1 mM | 0.7595 mL | 3.7976 mL | 7.5951 mL |
| 5 mM | 0.1519 mL | 0.7595 mL | 1.5190 mL |
| 10 mM | 0.0760 mL | 0.3798 mL | 0.7595 mL |
| 50 mM | 0.0152 mL | 0.0760 mL | 0.1519 mL |
Description
VcMMAE (mc-vc-PAB-MMAE), a MMAE derivative with valine-citrulline (Vc) linker,is an for antibody-drug conjugate (ADC) with potent antitumor activity. MMAE is a synthetic antineoplastic agent and can be efficiently released from VcMMAE in vitro and exert cytotoxic activity.
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