[CAS NO. 67953-08-6] GPNA (L-γ-Glutamyl-p-nitroanilide)
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PRODUCTS SPECIFICATIONS [67953-08-6]
Catalog
SLK-S6670
Brand
Selleck
CAS
67953-08-6
DESCRIPTION [67953-08-6]
Overview
| MDL | - |
|---|---|
| Molecular Weight | 303.7 |
| Molecular Formula | C11H14ClN3O5 |
| SMILES | N(=O)(=O)C1=CC=C(NC(CC[C@@H](C(O)=O)N)=O)C=C1.Cl |
For research use only.
Storage
3 years,-20°C,powder
1 years,-80°C,in solvent
1 years,-80°C,in solvent
Shipping
Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)
Preparing Stock Solutions
| 1 mg | 5 mg | 10 mg | |
| 1 mM | 3.2927 mL | 16.4636 mL | 32.9272 mL |
| 5 mM | 0.6585 mL | 3.2927 mL | 6.5854 mL |
| 10 mM | 0.3293 mL | 1.6464 mL | 3.2927 mL |
| 50 mM | - | - | - |
Description
GPNA (L-γ-Glutamyl-p-nitroanilide) is a potent and selective inhibitor of the glutamine (Gln) transporter with Ki of 55 µM.
Targets
| ASCT2 [1] (Cell-free assay) |
| 55 μM(Ki) |
In vitro
GPNA leads to a significant decrease in endometrial cancer cell growth and spheroid cross-sectional area.
References
Synonyms
L-Glutamine, N-(4-nitrophenyl)-, hydrochloride (1:1)
L-Glutamine, N-(4-nitrophenyl)-, monohydrochloride
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