[CAS NO. 565-73-1] Sodium oxamate
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PRODUCTS SPECIFICATIONS [565-73-1]
Store
Catalog
SLK-S6871
Brand
Selleck
CAS
565-73-1
DESCRIPTION [565-73-1]
Overview
| MDL | MFCD00044553 |
|---|---|
| Molecular Weight | 111.03 |
| Molecular Formula | C2H2NNaO3 |
| SMILES | C(C(O)=O)(N)=O.[Na] |
For research use only.
Storage
3 years,-20°C,powder
1 years,-80°C,in solvent
1 years,-80°C,in solvent
Shipping
Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)
Description
Sodium oxamate (SO, Aminooxoacetic acid, Oxamic acid) is an inhibitor of that specificly inhibits LDH‑A. Sodium oxamate (SO) induces G2/M cell cycle arrest via downregulation of the pathway and promotes through enhancement of mitochondrial generation.
In vitro
Sodium oxamate, a specific inhibitor of LDH-A, enhances the suppressive effects of PARP inhibitors on ovarian cancer without BRCA mutations, remarkably promoting the inhibitory effects of PARP inhibitors on wild-type BRCA ovarian cancer cells.
References
Synonyms
Acetic acid, 2-amino-2-oxo-, sodium salt (1:1)
Oxamic acid, sodium salt
Oxamic acid, monosodium salt
Acetic acid, aminooxo-, monosodium salt
Sodium oxamate
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