[CAS NO. 34233-69-7]  Clozapine N-oxide

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PRODUCTS SPECIFICATIONS [34233-69-7]

Distributor
Catalog
SLK-S6887
Brand
Selleck
CAS
34233-69-7

DESCRIPTION [34233-69-7]

Overview

MDL-
Molecular Weight342.82
Molecular FormulaC18H19ClN4O
SMILESCN1(=O)CCN(C=2C=3C(NC=4C(N2)=CC(Cl)=CC4)=CC=CC3)CC1

For research use only.

Storage

3 years,-20°C,powder
1 years,-80°C,in solvent

Shipping

Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)

Preparing Stock Solutions

1 mg5 mg10 mg
1 mM2.9170 mL14.5849 mL29.1698 mL
5 mM0.5834 mL2.9170 mL5.8340 mL
10 mM0.2917 mL1.4585 mL2.9170 mL
50 mM0.0583 mL0.2917 mL0.5834 mL

Description

Clozapine N-oxide (CNO) is a metabolite of Clozapine (GLXC-06516) and an agonist of . Clozapine is a potent antagonist and a selective agonist.

Targets

DREADD [1]Dopamine receptor [2]muscarinic M4 receptor [1]

In vitro

CNO is a synthetic small molecule actuator for muscarinic acetylcholine DREADDs.


Synonyms

5H-Dibenzo[b,e][1,4]diazepine, 8-chloro-11-(4-methyl-4-oxido-1-piperazinyl)-
5H-Dibenzo[b,e][1,4]diazepine, 8-chloro-11-(4-methyl-1-piperazinyl)-, N-oxide
8-Chloro-11-(4-methyl-4-oxido-1-piperazinyl)-5H-dibenzo[b,e][1,4]diazepine
Clozapine N-oxide