[CAS NO. 1227634-69-6]  GNF351

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PRODUCTS SPECIFICATIONS [1227634-69-6]

Catalog
SLK-S6926
Brand
Selleck
CAS
1227634-69-6

DESCRIPTION [1227634-69-6]

Overview

MDLMFCD23726597
Molecular Weight411.50
Molecular FormulaC24H25N7
SMILESCC1=CN=CC(C2=NC(NCCC3=CNC4=C3C=CC=C4)=C5N=CN(C(C)C)C5=N2)=C1

For research use only.

Storage

3 years,-20°C,powder
1 years,-80°C,in solvent

Shipping

Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)

Preparing Stock Solutions

1 mg5 mg10 mg
1 mM2.4301 mL12.1507 mL24.3013 mL
5 mM0.4860 mL2.4301 mL4.8603 mL
10 mM0.2430 mL1.2151 mL2.4301 mL
50 mM0.0486 mL0.2430 mL0.4860 mL

Description

GNF351 is a potent antagonist of . GNF351 interacts directly with the AHR ligand binding pocket and competes with a well-characterized photoaffinity AHR ligand for binding to the AHR with IC50 of 62 nM.

Targets

AhR [1]
(Cell-free assay)
62 nM