[CAS NO. 2009273-71-4]  GEN-6776

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PRODUCTS SPECIFICATIONS [2009273-71-4]

Store
Catalog
SLK-S6933
Brand
Selleck
CAS
2009273-71-4

DESCRIPTION [2009273-71-4]

Overview

MDLMFCD31657364
Molecular Weight348.40
Molecular FormulaC20H20N4O2
SMILESO=C(C1=CC=C(C2=C(CC)C(C3=CC=C(O)C=C3)=C(N)N=C2)C=N1)NC

For research use only.

Storage

3 years,-20°C,powder
1 years,-80°C,in solvent

Shipping

Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)

Preparing Stock Solutions

1 mg5 mg10 mg
1 mM2.8703 mL14.3513 mL28.7026 mL
5 mM0.5741 mL2.8703 mL5.7405 mL
10 mM0.2870 mL1.4351 mL2.8703 mL
50 mM0.0574 mL0.2870 mL0.5741 mL

Description

GNE-6776 is a potent, non-covalent, selective and orally bioavailable inhibitor of with IC50 of 1.34 μM and 0.61 μM for full length USP7 and USP7 catalytic domain, respectively.

Targets

USP7 catalytic domain [1]
(Cell-free assay)
full length USP7 [1]
(Cell-free assay)
0.61 μM1.34 μM