[CAS NO. 1507930-57-5]  Gap19

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PRODUCTS SPECIFICATIONS [1507930-57-5]

Catalog
SLK-S6946
Brand
Selleck
CAS
1507930-57-5

DESCRIPTION [1507930-57-5]

Overview

MDL-
Molecular Weight1161.44
Molecular FormulaC55H96N14O13
SMILES-

For research use only.

Storage

3 years,-20°C,powder
1 years,-80°C,in solvent

Shipping

Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)

Preparing Stock Solutions

1 mg5 mg10 mg
1 mM0.8610 mL4.3050 mL8.6100 mL
5 mM0.1722 mL0.8610 mL1.7220 mL
10 mM0.0861 mL0.4305 mL0.8610 mL
50 mM0.0172 mL0.0861 mL0.1722 mL

Description

Gap19 is a nonapeptide derived from the cytoplasmic loop (CL) of Cx43 and acts as a selective hemichannel blocker. Gap19 blocks Cx43 hemichannels without inhibiting gap junctions (GJs) at IC50 of 6.5 μM when applied intracellulary.

Targets

connexin 43 [1]