[CAS NO. 885434-70-8] HJC0350
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PRODUCTS SPECIFICATIONS [885434-70-8]
Catalog
SLK-S7500
Brand
Selleck
CAS
885434-70-8
DESCRIPTION [885434-70-8]
Overview
| MDL | MFCD05144768 |
|---|---|
| Molecular Weight | 277.38 |
| Molecular Formula | C15H19NO2S |
| SMILES | CC1=CN(S(=O)(C2=C(C)C=C(C)C=C2C)=O)C(C)=C1 |
For research use only.
Storage
3 years,-20°C,powder
1 years,-80°C,in solvent
1 years,-80°C,in solvent
Shipping
Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)
Preparing Stock Solutions
| 1 mg | 5 mg | 10 mg | |
| 1 mM | 3.6052 mL | 18.0258 mL | 36.0516 mL |
| 5 mM | 0.7210 mL | 3.6052 mL | 7.2103 mL |
| 10 mM | 0.3605 mL | 1.8026 mL | 3.6052 mL |
| 50 mM | 0.0721 mL | 0.3605 mL | 0.7210 mL |
Description
HJC0350 is a potent and selective inhibitor with of 0.3 μM, exhibiting no inhibition on Epac1.
Targets
| EPAC2 [1] |
| 0.3 μM |
In vitro
HJC0350 selectively blocks cAMP-induced EPAC2 activation but do not inhibit cAMP-mediated PKA activation. In HEK293/EPAC2-FL cells, HJC0350 also inhibits 007-AM mediated cellular activation of EPAC2.
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