[CAS NO. 1620401-82-2]  UNC0379

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PRODUCTS SPECIFICATIONS [1620401-82-2]

Catalog
SLK-S7570
Brand
Selleck
CAS
1620401-82-2

DESCRIPTION [1620401-82-2]

Overview

MDLMFCD28167817
Molecular Weight413.56
Molecular FormulaC23H35N5O2
SMILESCOC1=CC2=NC(N3CCCC3)=NC(NCCCCCN4CCCC4)=C2C=C1OC

For research use only.

Storage

3 years,-20°C,powder
1 years,-80°C,in solvent

Shipping

Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)

Preparing Stock Solutions

1 mg5 mg10 mg
1 mM2.4180 mL12.0901 mL24.1803 mL
5 mM0.4836 mL2.4180 mL4.8361 mL
10 mM0.2418 mL1.2090 mL2.4180 mL
50 mM0.0484 mL0.2418 mL0.4836 mL

Description

UNC0379 is a selective, substrate competitive inhibitor of with of 7.3 μM, high selectivity over 15 other methyltransferases.

Targets

SETD8 [1]
(Cell-free assay)
7.3 μM

In vitro

UNC0379 is competitive with the peptide substrate and noncompetitive with the cofactor SAM.