[CAS NO. 1622921-15-6] Remodelin hydrobromide
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PRODUCTS SPECIFICATIONS [1622921-15-6]
Store
Catalog
SLK-S7641
Brand
Selleck
CAS
1622921-15-6
DESCRIPTION [1622921-15-6]
Overview
| MDL | MFCD28137688 |
|---|---|
| Molecular Weight | 363.28 |
| Molecular Formula | C15H15BrN4S |
| SMILES | N#CC1=CC=C(C2=CSC(N/N=C3CCCC/3)=N2)C=C1.[H]Br |
For research use only.
Storage
3 years,-20°C,powder
1 years,-80°C,in solvent
1 years,-80°C,in solvent
Shipping
Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)
Preparing Stock Solutions
| 1 mg | 5 mg | 10 mg | |
| 1 mM | 2.7527 mL | 13.7635 mL | 27.5270 mL |
| 5 mM | 0.5505 mL | 2.7527 mL | 5.5054 mL |
| 10 mM | 0.2753 mL | 1.3763 mL | 2.7527 mL |
| 50 mM | 0.0551 mL | 0.2753 mL | 0.5505 mL |
Description
Remodelin hydrobromide (HBr) is a potent inhibitor.
Targets
| NAT10 [1] |
In vitro
Remodelin, via inhibition of NAT10, mediates nuclear shape rescue of LMNA depleted cells by microtubule reorganization, and improves nuclear shape and fitness of HGPS cells. Remodelin may thus provide opportunities for alleviating dystrophic and premature-ageing diseases.
References
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