[CAS NO. 1675201-83-8] BMS-1 (PD-1/PD-L1 inhibitor 1)
Please click "REQUEST A QUOTE" button if you need other sizes or custom synthesis
request a quote
If there is no stock, or you need other sizes or custom synthesis, please:
PRODUCTS SPECIFICATIONS [1675201-83-8]
Store
Catalog
SLK-S7911
Brand
Selleck
CAS
1675201-83-8
DESCRIPTION [1675201-83-8]
Overview
| MDL | MFCD28978741 |
|---|---|
| Molecular Weight | 475.58 |
| Molecular Formula | C29H33NO5 |
| SMILES | O=C([C@H]1N(CC2=C(OC)C=C(OCC3=C(C)C(C4=CC=CC=C4)=CC=C3)C=C2OC)CCCC1)O |
For research use only.
Storage
3 years,-20°C,powder
1 years,-80°C,in solvent
1 years,-80°C,in solvent
Shipping
Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)
Description
BMS-1 (PD-1/PD-L1 inhibitor 1, PD1-PDL1-IN1) is a small-molecule inhibitor of with of 6 nM.
Targets
| PD-1/PD-L1 interaction [1] (Cell-free assay) |
| 0.006 μM |
In vitro
PD-1/PD-L1 inhibitor 1 causes half-reduced cell viability at lower concentrations in triple-negative breast cancer (TNBC), activates ERK in MDA-MB-231 and MCF7, significantly increases IL-8 expression in MDA-MB-231 and HCC1806 when administrated in combination with ERK1/2 inhibitor, also potently downregulates the IL-8 expression to its half amount in MDA-MB-231.
References
Powered by Arctom Copyright © 2026 Arctom. All rights
reserved.