[CAS NO. 1162656-22-5] MCB-613
Please click "REQUEST A QUOTE" button if you need other sizes or custom synthesis
request a quote
If there is no stock, or you need other sizes or custom synthesis, please:
PRODUCTS SPECIFICATIONS [1162656-22-5]
Store
Catalog
SLK-S7913
Brand
Selleck
CAS
1162656-22-5
DESCRIPTION [1162656-22-5]
Overview
| MDL | MFCD01209975 |
|---|---|
| Molecular Weight | 304.39 |
| Molecular Formula | C20H20N2O |
| SMILES | O=C1C(CC(CC)CC1=CC2=CC=CN=C2)=CC3=CC=CN=C3 |
For research use only.
Storage
3 years,-20°C,powder
1 years,-80°C,in solvent
1 years,-80°C,in solvent
Shipping
Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)
Description
MCB-613 is a potent steroid receptor coactivator () stimulator.
Targets
| SRC [1] |
In vitro
MCB-613 selectively and reversibly binds to the RID of SRC-3, and selectively kills cancer cells including MCF-7 (breast), PC-3 (prostate), H1299 (lung), and HepG2 (liver) cells, without toxicity to mouse primary hepatocytes and mouse embryonic fibroblasts (MEFs). MCB-613 also increases SRCs’ interactions with other coactivators and markedly induces ER stress coupled to the generation of reactive oxygen species (ROS).
In vivo
In an MCF-7 breast cancer mouse xenograft model, MCB-613 (20 mg/kg, i.p.) significantly and dramatically inhibits the growth of the tumor while causing no obvious animal toxicity and body weight less.
Powered by Arctom Copyright © 2026 Arctom. All rights
reserved.