[CAS NO. 1448428-04-3]  Selonsertib (GS-4997)

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PRODUCTS SPECIFICATIONS [1448428-04-3]

Catalog
SLK-S8292
Brand
Selleck
CAS
1448428-04-3

DESCRIPTION [1448428-04-3]

Overview

MDLMFCD29920355
Molecular Weight445.49
Molecular FormulaC24H24FN7O
SMILESO=C(C1=CC(N2C=C(N=C2)C3CC3)=C(C=C1F)C)NC4=NC(C5=NN=CN5C(C)C)=CC=C4

For research use only.

Storage

3 years,-20°C,powder
1 years,-80°C,in solvent

Shipping

Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)

Description

Selonsertib (GS-4997) is a highly selective and potent once-daily oral inhibitor with potential anti-inflammatory, antineoplastic and anti-fibrotic activities.

Targets

ASK1 [3]
(Cell-free assay)
8.3(pIC50)

In vitro

Selonsertib (GS-4997) is a highly selective and potent once-daily oral ASK1 inhibitor with pIC50 of 8.3.