[CAS NO. 1010100-07-8]  CC-885

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PRODUCTS SPECIFICATIONS [1010100-07-8]

Catalog
SLK-S8300
Brand
Selleck
CAS
1010100-07-8

DESCRIPTION [1010100-07-8]

Overview

MDL-
Molecular Weight440.88
Molecular FormulaC22H21ClN4O4
SMILESO=C(NCC1=CC2=C(C(N(C(CC3)C(NC3=O)=O)C2)=O)C=C1)NC4=CC=C(C)C(Cl)=C4

For research use only.

Storage

3 years,-20°C,powder
1 years,-80°C,in solvent

Shipping

Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)

Preparing Stock Solutions

1 mg5 mg10 mg
1 mM2.2682 mL11.3410 mL22.6819 mL
5 mM0.4536 mL2.2682 mL4.5364 mL
10 mM0.2268 mL1.1341 mL2.2682 mL
50 mM0.0454 mL0.2268 mL0.4536 mL

Targets

CRBN [1]

In vitro

CC-885 selectively promotes CRBN- and p97-dependent PLK1 ubiquitination and degradation in non-small-cell lung cancer (NSCLC) cells.[1]