[CAS NO. 1196541-47-5]  GDC-0575 (ARRY-575)

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PRODUCTS SPECIFICATIONS [1196541-47-5]

Catalog
SLK-S8526
Brand
Selleck
CAS
1196541-47-5

DESCRIPTION [1196541-47-5]

Overview

MDL-
Molecular Weight378.27
Molecular FormulaC16H20BrN5O
SMILES-

For research use only.

Storage

3 years,-20°C,powder
1 years,-80°C,in solvent

Shipping

Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)

Description

GDC-0575 (ARRY-575, RG7741) is a potent and selective inhibitor with an IC50 of 1.2 nM.

Targets

Chk1 [1]
(Cell-free assay)
1.2 nM

In vitro

GDC-0575 enhances the cytotoxicity of Cytarabine (AraC) in vitro.