Overview
| MDL | - |
|---|
| Molecular Weight | 2010.15 |
|---|
| Molecular Formula | C92H120N24O26S |
|---|
| SMILES | - |
|---|
For research use only.
Storage
3 years,-20°C,powder
1 years,-80°C,in solvent
Shipping
Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)
Preparing Stock Solutions
| 1 mg | 5 mg | 10 mg |
| 1 mM | 0.4975 mL | 2.4874 mL | 4.9748 mL |
| 5 mM | 0.0995 mL | 0.4975 mL | 0.9950 mL |
| 10 mM | 0.0497 mL | 0.2487 mL | 0.4975 mL |
| 50 mM | - | - | - |
Description
CP2 is a cyclic peptide that inhibits the with IC50 values of 42 nM and 29 nM for and , respectively.
Targets
KDM4C [1] (Cell-free assay) | KDM4A [1] (Cell-free assay) |
| 29 nM | 42 nM |
In vitro
CP2 uniquely binds in the KDM4A substrate-binding pocket. It binds differently to, but competes with, histone substrates in the active site.