[CAS NO. 2375840-87-0]  NDI-091143

Ships within Stock Price Qty Total
$0.00
$0.00
Please click "REQUEST A QUOTE" button if you need other sizes or custom synthesis
request a quote
If there is no stock, or you need other sizes or custom synthesis, please:

PRODUCTS SPECIFICATIONS [2375840-87-0]

Catalog
SLK-S8878
Brand
Selleck
CAS
2375840-87-0

DESCRIPTION [2375840-87-0]

Overview

MDL-
Molecular Weight453.84
Molecular FormulaC20H14ClF2NO5S
SMILESO=C(OC)C1=CC(S(=O)(NC2=CC(C3=CC=CC=C3)=C(F)C=C2F)=O)=C(O)C(Cl)=C1

For research use only.

Storage

3 years,-20°C,powder
1 years,-80°C,in solvent

Shipping

Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)

Preparing Stock Solutions

1 mg5 mg10 mg
1 mM2.2034 mL11.0171 mL22.0342 mL
5 mM0.4407 mL2.2034 mL4.4068 mL
10 mM0.2203 mL1.1017 mL2.2034 mL
50 mM0.0441 mL0.2203 mL0.4407 mL

Description

NDI-091143 is a potent inhibitor of human with a Ki of 7.0 nM and an IC50 of 2.1 nM in the ADP-Glo assay.

Targets

ATP-citrate lyase [1]
(Cell-free assay)
7.0 nM(Ki)

In vitro

ACLY inhibitor NDI091143 exerts dose-dependent inhibition of T24 and T24T clonogenic survival.