[CAS NO. 1898207-64-1]  DS-1001b (DS 1001)

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PRODUCTS SPECIFICATIONS [1898207-64-1]

Store
Catalog
SLK-S8881
Brand
Selleck
CAS
1898207-64-1

DESCRIPTION [1898207-64-1]

Overview

MDL-
Molecular Weight608.92
Molecular FormulaC29H29Cl3FN3O4
SMILESCC(N)(C)C.O=C(O)/C=C/C1=CC=CC2=C1C(C)=CN2C(C3=C(C(C)(F)C)ON=C3C4=C(Cl)C=C(Cl)C=C4Cl)=O

For research use only.

Storage

3 years,-20°C,powder
1 years,-80°C,in solvent

Shipping

Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)

Preparing Stock Solutions

1 mg5 mg10 mg
1 mM1.6423 mL8.2113 mL16.4225 mL
5 mM0.3285 mL1.6423 mL3.2845 mL
10 mM0.1642 mL0.8211 mL1.6423 mL
50 mM---

Description

DS-1001b is an oral selective inhibitor of with potential antineoplastic activity and is designed to penetrate the blood-brain barrier.

Targets

IDH1 R132X [1]

In vitro

DS-1001b impairs the proliferation of IDH1 mutant chondrosarcoma cell lines and decreases 2-HG levels.