[CAS NO. 1382799-40-7]  MK-8719

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PRODUCTS SPECIFICATIONS [1382799-40-7]

Catalog
SLK-S8890
Brand
Selleck
CAS
1382799-40-7

DESCRIPTION [1382799-40-7]

Overview

MDL-
Molecular Weight268.28
Molecular FormulaC9H14F2N2O3S
SMILES-

For research use only.

Storage

3 years,-20°C,powder
1 years,-80°C,in solvent

Shipping

Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)

Preparing Stock Solutions

1 mg5 mg10 mg
1 mM3.7274 mL18.6372 mL37.2745 mL
5 mM0.7455 mL3.7274 mL7.4549 mL
10 mM0.3727 mL1.8637 mL3.7274 mL
50 mM0.0745 mL0.3727 mL0.7455 mL

Description

MK-8719 is a selective and potent small molecule inhibitor of the enzyme with ki of 7.9nM for hOGA.

Targets

hOGA [1]
(Cell-free assay)
7.9nM(Ki)

In vitro

In vitro, MK-8719 is a potent inhibitor of the human OGA enzyme with comparable activity against the corresponding enzymes from mouse, rat, and dog.