[CAS NO. 2242464-44-2] BAY 2416964
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PRODUCTS SPECIFICATIONS [2242464-44-2]
Catalog
SLK-S8995
Brand
Selleck
CAS
2242464-44-2
DESCRIPTION [2242464-44-2]
Overview
| MDL | - |
|---|---|
| Molecular Weight | 387.82 |
| Molecular Formula | C18H18ClN5O3 |
| SMILES | O=C(C1=CC(C2=CC=C(Cl)C=C2)=NN(C3=CN(C)N=C3)C1=O)N[C@@H](C)CO |
For research use only.
Storage
3 years,-20°C,powder
1 years,-80°C,in solvent
1 years,-80°C,in solvent
Shipping
Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)
Preparing Stock Solutions
| 1 mg | 5 mg | 10 mg | |
| 1 mM | 2.5785 mL | 12.8926 mL | 25.7852 mL |
| 5 mM | 0.5157 mL | 2.5785 mL | 5.1570 mL |
| 10 mM | 0.2579 mL | 1.2893 mL | 2.5785 mL |
| 50 mM | 0.0516 mL | 0.2579 mL | 0.5157 mL |
Description
BAY 2416964 (compound 192) is a potent and orally active antagonist of with IC50 of 341 nM. BAY 2416964 has the potential in the treatment of solid tumors.
Targets
| AhR [1] (Cell-free assay) |
| 341 nM |
In vitro
BAY 2416964 (Example 192) induces AHR-regulated gene CYP1A1 expression with IC50 of 4.30 nM in a human monocytic U937 cells.
References
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