[CAS NO. 118876-58-7] NBQX (FG9202)

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PRODUCTS SPECIFICATIONS [118876-58-7]

Catalog

SLK-S9686

Brand

Selleck

CAS

118876-58-7

DESCRIPTION [118876-58-7]

Overview

MDL	MFCD00270054
Molecular Weight	336.28
Molecular Formula	C12H8N4O6S
SMILES	S(N)(=O)(=O)C=1C=2C(=C3C(=CC2N(=O)=O)NC(=O)C(=O)N3)C=CC1

For research use only.

Storage

3 years,-20°C,powder
1 years,-80°C,in solvent

Shipping

Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)

Preparing Stock Solutions

Concentration Volume Mass	1 mg	5 mg	10 mg
1 mM	2.9737 mL	14.8686 mL	29.7371 mL
5 mM	0.5947 mL	2.9737 mL	5.9474 mL
10 mM	0.2974 mL	1.4869 mL	2.9737 mL
50 mM	0.0595 mL	0.2974 mL	0.5947 mL

Description

NBQX (FG9202, NNC 079202) is a highly selective and competitive antagonist of with anti-epileptic effect.

Targets

AMPAR ^[1]

In vitro

NBQX is highly selective in vitro. The IC50 value for inhibition of AMPA-evoked inward currents is 0.4 μM for NBQX. While NBQX inhibits NMDA-induced currents with IC50 value of 60 μM.

References

[1] Wen Chen, et al. PLoS One. 2016 Nov 23;11(11):e0166672.
[2] C Mathiesen, et al. Eur J Pharmacol. 1998 Jul 24;353(2-3):159-67.

Synonyms

Benzo[f]quinoxaline-7-sulfonamide, 1,2,3,4-tetrahydro-6-nitro-2,3-dioxo-

1,2,3,4-Tetrahydro-6-nitro-2,3-dioxobenzo[f]quinoxaline-7-sulfonamide

FG 9202

NBQX