[CAS NO. 1970972-74-7] Danicamtiv (MYK-491)
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PRODUCTS SPECIFICATIONS [1970972-74-7]
Catalog
SLK-S9948
Brand
Selleck
CAS
1970972-74-7
DESCRIPTION [1970972-74-7]
Overview
| MDL | - |
|---|---|
| Molecular Weight | 435.42 |
| Molecular Formula | C16H20F3N5O4S |
| SMILES | - |
For research use only.
Storage
3 years,-20°C,powder
1 years,-80°C,in solvent
1 years,-80°C,in solvent
Shipping
Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)
Preparing Stock Solutions
| 1 mg | 5 mg | 10 mg | |
| 1 mM | 2.2966 mL | 11.4832 mL | 22.9663 mL |
| 5 mM | 0.4593 mL | 2.2966 mL | 4.5933 mL |
| 10 mM | 0.2297 mL | 1.1483 mL | 2.2966 mL |
| 50 mM | 0.0459 mL | 0.2297 mL | 0.4593 mL |
Targets
| cardiac myosin [1] |
In vitro
Danicamtiv metabolism pathways in vitro included CYP-mediated amide-cleavage, N-demethylation, as well as isoxazole- and piperidine-ring-opening.Danicamtiv show high permeability and no efflux in a Caco-2 cell line.[2]
References
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