Acrylamide-PEG-Alkyne (ACA-PEG-Alkyne) is a linear bifunctional PEG reagent with an acrylamide group at one end and an alkyne group at the other. The acrylamide group can undergo radical initiator-induced polymerization or UV light-sensitive photopolymerization to form crosslinked polymer networks and PEG hydrogels. The alkyne group enables copper-catalyzed Click Chemistry with azide-bearing compounds, facilitating bioconjugation and surface modification. This versatile reagent is widely used in biomedical research, drug delivery systems, and the development of advanced biomaterials.
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