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AACR 2026 Part 2: Small-Molecule Oncology Breakthroughs

🧪 AACR 2026 continues to deliver — Part 2 spotlight! 3 more cutting‑edge small‑molecule breakthroughs targeting therapy resistance, cell cycle dysregulation, and hard‑to‑treat leukemia.
🧪 AACR 2026 continues to deliver — Part 2 spotlight!
3 more cutting‑edge small‑molecule breakthroughs targeting therapy resistance, cell cycle dysregulation, and hard‑to‑treat leukemia.
🔥 Highlights:
1.ECI‑830: Highly selective CDK2 inhibitor overcoming CDK4/6
resistance in HR+/HER2‑ breast cancer.
2.CID‑078: First‑in‑class macrocyclic cell cycle inhibitor for RB1‑deficient / E2F‑activated aggressive tumors.
3.AMX‑883: DCAF16‑dependent BRD9 degrader unlocking a new differentiation paradigm in AML.
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#AACR2026 #SmallMolecule #DrugDiscovery #Proteindegradation #BuildingBlocks #Oncology #MedicinalChemistry #CustomSynthesis #ChemScene
Originally posted on LinkedIn: 2026-05-09 (UTC; date derived from the LinkedIn activity ID).
Source: ChemScene on LinkedIn







